acetaminophen, diclofenac, chlorpheniramine and magnesium trisilicate in one dosage form; oral tablet formulation and physicochemical evaluation

Formulation Development of Solid Oral Dosage Form

6.1 Literature review matrix Taha E. et al (2015) evaluated Diclofenac Sodium (DS) matrix tablets prepared by direct compression method under different compression forces using ethyl cellulose as matrix forming material. The produced tablets were characterized for hardness, friability, drug content, weight variations and in vitro drug release. Incompatibility study carried out using DSC FT-IR s...

Design, Formulation, and Physicochemical Evaluation of Montelukast Orally Disintegrating Tablet

BACKGROUND Orally disintegrating tablets (ODTs) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. These tablets have advantages, particularly good applications for children and old patients who have a complication in chewing or swallowing solid dosage forms. The aim of this study was to design, formulate, and evaluate the physicochemical properties of 5 mg mon...

Simultaneous Uv-spectrophotometric Estimation of Diclofenac and Tolperisone Hydrochloride in Tablet Dosage Form

Diclofenac sodium is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. Tolperisone hydrochloride is a piperidine derivative, is a centrally-acting muscle relaxant. Two simple, accurate and economic methods; Q analysis and first order derivative method have been described for the simultaneous spectrophotometric es...

design, formulation and physicochemical evaluation of acetaminophen effervescent tablets

background : the main objective of this study was to design, formulate and evaluate the physicochemical properties of 500 mg acetaminophen effervescent tablets, in order to accelerate its analgesic and antipyretic effects in patients with pill swallowing problems. methods : formulations with 500 mg of acetaminophen were prepared with effervescent bases including tartaric acid, citric acid, sodi...

design, formulation, and physicochemical evaluation of montelukast orally disintegrating tablet

background: orally disintegrating tablets (odts) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. these tablets have advantages, particularly good applications for children and old patients who have a complication in chewing or swallowing solid dosage forms. the aim of this study was to design, formulate, and evaluate the physicochemical properties of 5 mg mo...

formulation and physicochemical evaluation of rizatriptan orally disintegrating tablet